Atypical Alterations of cerebrospinal fluid in Guillain Barré Syndrome: Cases Reports.

Authors

  • Laura Zelada-Ríos Instituto Nacional de Ciencias Neurológicas. Lima, Perú.
  • Erik Guevara-Silva Centro de Investigación Básica en Demencias y Enfermedades Desmielinizantes del Sistema Nervioso, Instituto Nacional de Ciencias Neurológicas. Lima, Perú.
  • Sheila Castro-Suarez Centro de Investigación Básica en Demencias y Enfermedades Desmielinizantes del Sistema Nervioso, Instituto Nacional de Ciencias Neurológicas. Lima, Perú. / Atlantic Fellow for Equity in Brain Health, University of California San Francisco, Department of Neurology, University of California. San Francisco, CA, USA.
  • César Caparó-Zamalloa Centro de Investigación Básica en Demencias y Enfermedades Desmielinizantes del Sistema Nervioso, Instituto Nacional de Ciencias Neurológicas. Lima, Perú.
  • María Meza-Vega Centro de Investigación Básica en Demencias y Enfermedades Desmielinizantes del Sistema Nervioso, Instituto Nacional de Ciencias Neurológicas. Lima, Perú.

DOI:

https://doi.org/10.20453/rnp.v84i1.3939

Keywords:

Disociación albuminocitológica, hipoglucorraquia, líquido cefalorraquídeo, pleocitosis, poliradiculopatía aguda axonal, Síndrome de Guillain-Barré

Abstract

Guillain-Barré syndrome shows a cyto-albuminologic dissociation in most patients. Pleocytosis or hypoglycorrhachia may defer the diagnosis, a reason for which an infectious etiology must be ruled out. Three cases of Guillain- Barré are described, whose cerebrospinal fluid tests showed limphocytic pleocytosis and persistently elevated protein concentration, while one of the cases also showed hypoglycorrhachia, and the classic cyto-albuminologic dissociation was only demonstrated in subsequent analysis. The neurophysiologic evaluation revealed an axonal disruption in all the patients. The atypical alterations in the context of acute flaccid paralysis warrant a retesting of the cerebrospinal fluid in order to rule out other etiologies, but without postponing the start of treatment.

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Published

2021-04-08

How to Cite

1.
Zelada-Ríos L, Guevara-Silva E, Castro-Suarez S, Caparó-Zamalloa C, Meza-Vega M. Atypical Alterations of cerebrospinal fluid in Guillain Barré Syndrome: Cases Reports. Rev Neuropsiquiatr [Internet]. 2021 Apr. 8 [cited 2024 May 18];84(1):64-8. Available from: https://revistas.upch.edu.pe/index.php/RNP/article/view/3939

Issue

Vol. 84 No. 1 (2021): January - March

Section

CASE REPORTS

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