COVID-19 y coma mixedematoso: reporte de dos casos y revisión de literatura
DOI:
https://doi.org/10.20453/rmh.v37i2.6381Palavras-chave:
hipotiroidismo, COVID-19, mortalidadResumo
El coma mixedematoso (CM) es una condición rara de alta mortalidad en pacientes con hipotiroidismo. Se reportan dos casos tratados en un hospital de tercer nivel en Lima, Perú, durante el periodo de 2020 a 2021. Ambas pacientes obtuvieron una puntuación diagnóstica en el score de Popoveniuc et al. mayor o igual a 60. Los casos cumplieron criterios de severidad para COVID-19. Presentaron hipotermia y bradicardia tras la intubación y administración de sedación y analgesia. Aún se desconoce cómo el SARS-CoV-2 desencadenaría el CM. Existe evidencia que sugiere una relación bioquímica e inmunológica entre este virus y la función tiroidea. La enfermedad tiroidea y el hipotiroidismo se asocian a mal pronóstico en la COVID-19. El objetivo del reporte fue describir la mayor incidencia de CM asociada a la infección por SARS-Cov-2 durante la pandemia de COVID-19.
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Copyright (c) 2026 María Jesús Poma-Rueda, Andrea Gómez de la Torre-del Carpio, Víctor Hugo Noriega-Ruiz, Jessica Faustor-Sánchez, Miluska Huachín-Soto
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