Study of nerve conduction in a population residing at high altitude

Authors

  • Charles Huamaní Universidad Andina del Cusco. Cusco, Perú.
  • Carlos Pérez-Alviz Universidad Andina del Cusco. Cusco, Perú. / Hospital Nacional Adolfo Guevara Velasco. Cusco, Perú.
  • Juan Acuña-Mamani Universidad Andina del Cusco. Cusco, Perú. / Hospital Nacional Adolfo Guevara Velasco. Cusco, Perú.
  • Víctor Oré-Montalvo Universidad Andina del Cusco. Cusco, Perú. / Hospital Nacional Adolfo Guevara Velasco. Cusco, Perú.
  • William Bayona-Pancorbo Hospital Nacional Adolfo Guevara Velasco. Cusco, Perú.
  • Gladys Mateos-Loaiza Hospital Nacional Adolfo Guevara Velasco. Cusco, Perú.
  • Daniela Collazos-Cachique Universidad Andina del Cusco. Cusco, Perú.

DOI:

https://doi.org/10.20453/rnp.v87i3.5243

Keywords:

neurophysiology, altitude, normal reference values

Abstract

Objective: To determine the normal values of nerve conduction speed (VCN, acronym in Spanish) parameters from people residing in a city localized at highaltitude. Material and methods: Analytical observational study of people without a comorbid history, residing in Cusco, a city located at 3399 meters above sea level. The motor VCN of the median, ulnar, common peroneal, tibial, and the sensory VCN of the median, ulnar, and sural nerves, their latencies and amplitudes, were evaluated. Results: The study included 56 participants, with a median age of 24 (22-26) years. The latencies of the median, ulnar, and anterior tibial nerves were <5 m/s, and of the peroneal nerves were >5 m/s. The amplitudes of the motor nerves were greater than 5mV and the sensory nerves were above 20μV; the motor velocities were greater than 50m/s, and the sensory nerves were greater than 45m/s. Conclusion: Figures are presented reflecting local VCN reference values, obtained from a young adult population residing in high altitude localities.

Downloads

Download data is not yet available.

Author Biographies

Charles Huamaní, Universidad Andina del Cusco. Cusco, Perú.

  

Carlos Pérez-Alviz, Universidad Andina del Cusco. Cusco, Perú. / Hospital Nacional Adolfo Guevara Velasco. Cusco, Perú.

  

Juan Acuña-Mamani, Universidad Andina del Cusco. Cusco, Perú. / Hospital Nacional Adolfo Guevara Velasco. Cusco, Perú.

  

Víctor Oré-Montalvo, Universidad Andina del Cusco. Cusco, Perú. / Hospital Nacional Adolfo Guevara Velasco. Cusco, Perú.

  

William Bayona-Pancorbo, Hospital Nacional Adolfo Guevara Velasco. Cusco, Perú.

  

Gladys Mateos-Loaiza, Hospital Nacional Adolfo Guevara Velasco. Cusco, Perú.

  

Daniela Collazos-Cachique, Universidad Andina del Cusco. Cusco, Perú.

  

References

Elafros MA, Kvalsund MP, Callaghan BC. The global burden of polyneuropathy—In need of an accurate assessment. JAMA Neurol [Internet]. 2022; 79(6): 537-538. Disponible en: https://doi.org/10.1001/jamaneurol.2022.0565

Mirian A, Aljohani Z, Grushka D, Florendo-Cumbermack A. Diagnosis and management of patients with polyneuropathy. CMAJ [Internet]. 2023; 195(6): E227-E233. Disponible en: https://doi.org/10.1503/cmaj.220936

Huynh W, Kiernan MC. Nerve conduction studies. Aust Fam Physician [Internet]. 2011; 40(9): 693-697. Disponible en: https://www.racgp.org.au/getattachment/629d74e6-4c1f-4690-b368-d1b8606ffc8f/Nerve-conduction-studies.aspx

Preston DC, Shapiro BE. Electromyography and Neuromuscular Disorders: Clinical-Electrophysiologic Correlations. Elsevier Health Sciences; 2005.

Uncini A, Santoro L. The electrophysiology of axonal neuropathies: more than just evidence of axonal loss. Clin Neurophysiol [Internet]. 2020; 131(10): 2367-2374. Disponible en: https://doi.org/10.1016/j.clinph.2020.07.014

Dillingham T, Chen S, Andary M, Buschbacher R, Del Toro D, Smith B, et al. Establishing highquality reference values for nerve conduction studies: a report from the normative data task force of the American Association of Neuromuscular & Electrodiagnostic Medicine. Muscle Nerve [Internet]. 2016; 54(3): 366-370. Disponible en: https://doi.org/10.1002/mus.25204

Chen S, Andary M, Buschbacher R, Del Toro D, Smith B, So Y, et al. Electrodiagnostic reference values for upper and lower limb nerve conduction studies in adult populations. Muscle Nerve [Internet]. 2016; 54(3): 371-377. Disponible en: https://doi.org/10.1002/mus.25203

Llamoca V, Mas G, Ortiz P. Características clínicas de los pacientes con diagnóstico electrofisiológico de síndrome de túnel del carpo en la atención ambulatoria del Hospital Nacional Arzobispo Loayza en el período 2010-2011. Rev Soc Per Med Interna [Internet]. 2016; 29(1): 14-21. Disponible en: https://medicinainterna.net.pe/images/REVISTAS/2016/numero_1/articulo_original2.pdf

Portillo R, Lira D, Quiñónez M. Evaluación neurofisiológica y clínica en pacientes con diabetes mellitus. An Fac Med Uni Nac Mayor San Marcos [Internet]. 2005; 66: 11-18. Disponible en: https://doi.org/10.15381/anales.v66i1.1334

Portillo R, Salazar M, Huertas MA. Síndrome del túnel del carpo: correlación clínica y neurofisiológica. An Fac Med Uni Nac Mayor San Marcos [Internet]. 2004; 65(4): 247-254. Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1025-55832004000400006

Kim JY, Kim E, Shim HS, Lee JH, Lee GJ, Kim K, et al. Reference standards for nerve conduction studies of individual nerves of lower extremity with expanded uncertainty in healthy Korean adults. Ann Rehabil Med [Internet]. 2022; 46(1): 9-23. Disponible en: https://doi.org/10.5535%2Farm.21170

Shah SK, Subedi P, Dhakal R, Ghale S, Khatiwada P. Nerve conduction and surface electromyography of physically active healthy medical undergraduates of Nepal. Int J Sci Health Res [Internet]. 2022; 7(3): 242-249. Disponible en: https://doi.org/10.52403/ijshr.20220735

Esteves EA, Guio SP, De los Reyes-Guevara CA, Cantor E, Habeych ME, Malagón AL. Reference values of upper extremity nerve conduction studies in a Colombian population. Clin Neurophysiol Pract [Internet]. 2020; 5: 73-78. Disponible en: https://doi.org/10.1016/j.cnp.2020.02.001

Shivji Z, Jabeen A, Awan S, Khan S. Developing normative reference values for nerve conduction studies of commonly tested nerves among a sample Pakistani population. J Neurosci Rural Pract [Internet]. 2019; 10(2): 178-184. Disponible en: https://doi.org/10.4103/jnrp.jnrp_370_18

Erken HA, Erken G, Çolak R, Genç O. Exercise and DHA prevent the negative effects of hypoxia on EEG and nerve conduction velocity. High Alt Med Biol [Internet]. 2013; 14(4): 360-366. Disponible en: https://doi.org/10.1089/ham.2012.1125

Rana PV. Neurological syndromes at high altitude part-II. Ann Neurosci [Internet]. 2010; 12(3): 60-66. Disponible en: https://annalsofneurosciences.org/journal/index.php/annal/article/viewArticle/194/480

Gaur P, Sartmyrzaeva M, Maripov A, Muratali Uulu K, Saini S, Ray K, et al. Cardiac acclimatization at high altitude in two different ethnicity groups. High Alt Med Biol [Internet]. 2021; 22(1): 58-69. Disponible en: https://doi.org/10.1089/ham.2020.0035

Fong SY, Goh KJ, Shahrizaila N, Wong KT, Tan CT. Effects of demographic and physical factors on nerve conduction study values of healthy subjects in a multi‐ethnic Asian population. Muscle Nerve [Internet]. 2016; 54(2): 244-248. Disponible en: https://doi.org/10.1002/mus.25029

Stetson DS, Albers JW, Silverstein BA, Wolfe RA. Effects of age, sex, and anthropometric factors on nerve conduction measures. Muscle Nerve [Internet]. 1992; 15(10): 1095-1104. Disponible en: https://doi.org/10.1002/mus.880151007

Rivner MH, Swift TR, Malik K. Influence of age and height on nerve conduction. Muscle Nerve [Internet]. 2001; 24(9): 1134-1141. Disponible en: https://doi.org/10.1002/mus.1124

Published

2024-09-30

How to Cite

1.
Huamaní C, Pérez-Alviz C, Acuña-Mamani J, Oré-Montalvo V, Bayona-Pancorbo W, Mateos-Loaiza G, et al. Study of nerve conduction in a population residing at high altitude. Rev Neuropsiquiatr [Internet]. 2024 Sep. 30 [cited 2025 Dec. 7];87(3):208-14. Available from: https://revistas.upch.edu.pe/index.php/RNP/article/view/5243

Issue

Section

ORIGINAL ARTICLE

Most read articles by the same author(s)