Use of ketamine in refractory depression in an adolescent patient: Case report

Authors

DOI:

https://doi.org/10.20453/rnp.v88i1.5914

Keywords:

depression, ketamine, adolescent psychiatry, antidepressive agents, refractory period, psychological

Abstract

Refractory depression is defined as a depressive disorder that does not respond to psychotherapy and two periods of pharmacological management. During adolescence, depression may have different manifestations than in adults, with therapeutic interventions based on the same premise but with variations for each age group. The prevalence of refractory depression is showing a progressive increase, a reason for which the search for more effective management is fundamental. In the midst of the initiatives to address it, the use of ketamine has been proposed, and several authors have detailed different therapeutic doses, duration of treatment and adverse effects. We present the case of a patient with long-term depression, who had undergone multiple therapeutic interventions, without symptomatic control, and who is currently receiving a ketamine regimen with promising results.

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Author Biographies

Juan David Ríos Restrepo, Hospital Regional de la Orinoquia. Yopal, Colombia.

Medico Interno Hospital Regional de la Orinoquia 

Elvia Elena Pardo Cely, Hospital Regional de la Orinoquia. Yopal, Colombia.

Medico psiquiatra de Hospital Regional de la Orinoquia

Omar Luis Pérez Caldera, Hospital Regional de la Orinoquia. Yopal, Colombia.

Medico Interno Hospital Regional de la Orinoquia

Lorena García Agudelo, Hospital Regional de la Orinoquia. Yopal, Colombia.

Medico epidemióloga líder de equipo de investigacion del Hospital Regional de la Orinoquia  

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Published

2025-03-28

How to Cite

1.
Ríos Restrepo JD, Pardo Cely EE, Pérez Caldera OL, García Agudelo L. Use of ketamine in refractory depression in an adolescent patient: Case report. Rev Neuropsiquiatr [Internet]. 2025 Mar. 28 [cited 2025 Dec. 7];88(1):42-6. Available from: https://revistas.upch.edu.pe/index.php/RNP/article/view/5914

Issue

Section

CASE REPORT