Utilidad del índice triglicéridos/HDL-C desde los primeros años de vida en el diagnóstico de síndrome metabólico en niños obesos

  • Emilio Cabello
  • Melissa Martínez
  • Ysel Cabrera
  • Susan Villafuerte
  • Isolda González
Palabras clave: Índice TG/HDL-C, síndrome metabólico, niños

Resumen

Objetivo: Determinar la utilidad del índice triglicéridos/HDL-C (TG/HDL-C) para el diagnóstico de síndrome metabólico (SM) en niños obesos de 2 a 14 años. Material y métodos: Estudio transversal tipo prueba de diagnóstico. Fueron incluidos 360 niños obesos exógenos (199M/161F), divididos en tres grupos etarios: 2 a <6 años, 6 a <10 años y 10 a 14 años. Se definió SM según los criterios de la International Diabetes Federation y se evaluó al índice TG/HDL-C como diagnóstico en dos puntos de corte: ≥2,32 y ≥3,5, en cada grupo etario. Se aplicó Chi cuadrado, considerándose significativo p<0,05. Se determinó la sensibilidad, especificidad y valores predictivos positivo y negativo, para cada punto de corte. Resultados: La frecuencia de SM fue 15,79% de 2 a <6 años, 20,25% de 6 a <10 años, 19,63% de 10 a 14 años. En los niños con SM el 97,1% presentó HDL bajo, 83,8% triglicéridos elevados. Se encontró diferencia significativa en la frecuencia del índice TG/HDL-C en ambos puntos de corte, entre los niños con y sin SM en todos los grupos etarios. La sensibilidad para ambos puntos de corte fue alta (86-100%) y la especificidad fue mejor para el punto de corte ≥3,5 (72-80%). Conclusiones: El índice TG/HDL-C ≥3,5 representaría un marcador sensible y específico para el diagnóstico de síndrome metabólico desde los primeros años de vida.

Citas

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Publicado
2020-01-13
Cómo citar
1.
Cabello E, Martínez M, Cabrera Y, Villafuerte S, González I. Utilidad del índice triglicéridos/HDL-C desde los primeros años de vida en el diagnóstico de síndrome metabólico en niños obesos. Revista Medica Herediana [Internet]. 13ene.2020 [citado 27ene.2022];30(4):249-55. Available from: https://revistas.upch.edu.pe/index.php/RMH/article/view/3660
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INVESTIGACION ORIGINAL