Revisión actualizada de recomendaciones para el tratamiento de la esquizofrenia en un instituto especializado: enfoque en terapias farmacológicas y psicosociales

Autores/as

  • Joshep Revilla-Zúñiga Universidad Peruana Cayetano Heredia, Facultad de Medicina Alberto Hurtado. Lima, Perú. / Contextual Roots. Lima, Perú. https://orcid.org/0000-0003-3224-3763
  • Abel Sagástegui-Soto Universidad Peruana Cayetano Heredia, Facultad de Medicina Alberto Hurtado. Lima, Perú. / Instituto Nacional de Salud Mental «Honorio Delgado-Hideyo Noguchi». Lima, Perú.
  • María Carazas-Vera Instituto Nacional de Salud Mental «Honorio Delgado-Hideyo Noguchi». Lima, Perú. https://orcid.org/0009-0003-5518-7239
  • Alfredo Saavedra-Castillo Universidad Peruana Cayetano Heredia, Facultad de Medicina Alberto Hurtado. Lima, Perú. / Instituto Nacional de Salud Mental «Honorio Delgado-Hideyo Noguchi». Lima, Perú.

DOI:

https://doi.org/10.20453/rnp.v88i2.6248

Palabras clave:

trastornos esquizofrénicos, psicosis paranoides, niveles de atención de salud, servicios de salud, mejores prácticas

Resumen

La esquizofrenia es un trastorno mental complejo y heterogéneo. El artículo presenta una revisión actualizada de las principales recomendaciones farmacológicas y psicosociales en el manejo de los pacientes adultos con esquizofrenia en un establecimiento de salud de nivel III-2 en el Perú. Se trata de una revisión no sistemática de la literatura en PubMed/MEDLINE, Scopus, EMBASE, Cochrane Library, Science Direct y Google Scholar. La esquizofrenia en el adulto requiere el abordaje farmacológico con antipsicóticos que pueden ser usados por vía oral, vía parenteral de acción rápida o vía parenteral de acción prolongada. Antes de su inicio y durante el tratamiento, se recomiendan exámenes basales periódicos. El uso de escalas permite evaluar la respuesta antipsicótica. Se recomienda evaluar regularmente los efectos colaterales/adversos de estos psicofármacos, tales como los síntomas extrapiramidales. Para el tratamiento de la esquizofrenia refractaria, se recomienda el uso de clozapina. En el abordaje psicoterapéutico, destaca la terapia cognitivo-conductual en sus modalidades individual y grupal. El manejo de la esquizofrenia requiere un abordaje farmacológico individualizado y otro, no farmacológico, que involucre a la persona y su contexto social.

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Biografía del autor/a

Joshep Revilla-Zúñiga, Universidad Peruana Cayetano Heredia, Facultad de Medicina Alberto Hurtado. Lima, Perú. / Contextual Roots. Lima, Perú.

          

Abel Sagástegui-Soto, Universidad Peruana Cayetano Heredia, Facultad de Medicina Alberto Hurtado. Lima, Perú. / Instituto Nacional de Salud Mental «Honorio Delgado-Hideyo Noguchi». Lima, Perú.

1 Universidad Peruana Cayetano Heredia, Facultad de Medicina Alberto Hurtado, Lima, Perú.

2 Instituto Nacional de Salud Mental “Honorio Delgado-Hideyo Noguchi”, Lima, Perú.

a Médico psiquiatra

María Carazas-Vera, Instituto Nacional de Salud Mental «Honorio Delgado-Hideyo Noguchi». Lima, Perú.

2 Instituto Nacional de Salud Mental “Honorio Delgado-Hideyo Noguchi”, Lima, Perú.

a Médico psiquiatra

Alfredo Saavedra-Castillo, Universidad Peruana Cayetano Heredia, Facultad de Medicina Alberto Hurtado. Lima, Perú. / Instituto Nacional de Salud Mental «Honorio Delgado-Hideyo Noguchi». Lima, Perú.

1 Universidad Peruana Cayetano Heredia, Facultad de Medicina Alberto Hurtado, Lima, Perú.

2 Instituto Nacional de Salud Mental “Honorio Delgado-Hideyo Noguchi”, Lima, Perú.

a Médico psiquiatra

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2025-06-26

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1.
Revilla-Zúñiga J, Sagástegui-Soto A, Carazas-Vera M, Saavedra-Castillo A. Revisión actualizada de recomendaciones para el tratamiento de la esquizofrenia en un instituto especializado: enfoque en terapias farmacológicas y psicosociales. Rev Neuropsiquiatr [Internet]. 26 de junio de 2025 [citado 7 de diciembre de 2025];88(2):147-6. Disponible en: https://revistas.upch.edu.pe/index.php/RNP/article/view/6248

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