Functional rehabilitation through occupational therapy for individuals with Guillain–Barré syndrome: a scoping review
DOI:
https://doi.org/10.20453/rhr.v8i2.7569Keywords:
Guillain–Barré syndrome, occupational therapy, rehabilitation, functionality, social participationAbstract
The objective of this review is to analyze and synthesize recent scientific evidence on occupational therapy interventions in the rehabilitation of individuals with Guillain–Barré syndrome. A scoping review was conducted following the PRISMA-ScR guidelines. The literature search was performed in PubMed/MEDLINE, Scopus, and Web of Science Core Collection, including studies published between 2023 and 2025. Studies addressing rehabilitation processes or occupational therapy interventions in populations diagnosed with Guillain–Barré syndrome were included, using a qualitative narrative synthesis. Nine studies were identified, with a predominance of descriptive designs and case reports. Findings indicate that occupational therapy is primarily integrated during the subacute and chronic phases of the rehabilitation process. Interventions focused on activities of daily living training, upper extremity function, environmental adaptation, and social reintegration. The findings reveal a predominance of descriptive study designs and case reports. Although occupational therapy provides relevant contributions to the functional rehabilitation of individuals with Guillain–Barré syndrome, the available scientific evidence is still limited. Therefore, future research should be strengthened through studies with greater methodological rigor.
Downloads
References
Van Doorn PA, Van den Bergh P, Hadden RD, Avau B, Vankrunkelsven P, Attarian S, et al. European Academy of Neurology/Peripheral Nerve Society guideline on diagnosis and treatment of Guillain-Barré syndrome. Eur J Neurol [Internet]. 2023; 30(12): 3646-3674. Disponible en: https://doi.org/10.1111/ene.16073
Khan SA, Das PR, Nahar Z, Rahman SM. An updated review on Guillain-Barré syndrome: challenges in infection prevention and control in low- and middle-income countries. SAGE Open Med [Internet]. 2024; 12: 20503121241239538. Disponible en: https://doi.org/10.1177/20503121241239538
Shahrizaila N, Lehmann HC, Kuwabara S. Guillain-Barré syndrome. Lancet [Internet]. 2021; 397(10280): 1214-1228. Disponible en: https://doi.org/10.1016/s0140-6736(21)00517-1
Bellanti SR, Rinaldi S. Guillain-Barré syndrome: a comprehensive review. Eur J Neurol [Internet]. 2024; 31(8): e16365. Disponible en: https://doi.org/10.1111/ene.16365
Yousef NM, Adejumo DK, Hazari A, Kandakurti PK. A structured rehabilitation program for functional recovery in Guillain-Barré syndrome: a case report. J Med Case Rep [Internet]. 2025; 19(1): 450. Disponible en: https://doi.org/10.1186/s13256-025-05545-z
Leonhard SE, Mandarakas MR, Gondim FA, Bateman K, Ferreira ML, Cornblath DR, et al. Diagnosis and management of Guillain-Barré syndrome in ten steps. Nat Rev Neurol [Internet]. 2019; 15: 671-683. Disponible en: https://doi.org/10.1038/s41582-019-0250-9
Kiper P, Chevrot M, Godart J, Cieślik B, Kiper A, Regazzetti M, et al. Physical exercise in Guillain-Barré syndrome: a scoping review. J Clin Med [Internet]. 2025; 14(8): 2655. Disponible en: https://doi.org/10.3390/jcm14082655
World Federation of Occupational Therapists. Position statement: Occupational Therapy and Rehabilitation [Internet]. WFOT; 2019. Disponible en: https://wfot.org/resources/occupational-therapy-and-rehabilitation
Houlahan M, Gintings N, Burdon M, Ashby S. An exploratory international survey of the assessments and interventions used by occupational therapists and physiotherapists during the hospitalization of people with Guillain-Barré syndrome. Nurs Health Sci [Internet]. 2023; 25(3): 804-813. Disponible en: https://doi.org/10.1111/nhs.13022
Clarkson S, Fisher A, McFadden S, Swanson P, Whitlow M, Smallfield S. Occupational Therapy Interventions to Optimize Functional Use of the Upper Extremity Following Peripheral Nerve Injury: A systematic review [Internet]. Omaha (NE): University of Nebraska Medical Center; 2022. Disponible en: https://digitalcommons.unmc.edu/cahp_ot_sysrev/4/
GBS-CIDP Foundation International. About GBS/CIDP Foundation International [Internet]. Narberth (PA): GBS-CIDP Foundation International; [s. f.]. Disponible en: https://rarediseases.org/organizations/gbs-cidp-foundation-international/
Coraci D, Romano M, Ragazzo L, Restivo DA, Cipriani M, Gottardello F, et al. Rehabilitation of peripheral neuropathies: from lexical analysis of the literature to identification of clinical protocols. J Clin Med [Internet]. 2023; 12(18): 5879. Disponible en: https://doi.org/10.3390/jcm12185879
Pearce LM, Pryor J, Redhead J, Sherrington C, Hassett L. Advanced technology in a real-world rehabilitation setting: longitudinal Observational Study on Clinician Adoption and Implementation. J Med Internet Res [Internet]. 2024; 26: e60374. Disponible en: https://doi.org/10.2196/60374
Bhagwat AP, Sharath H, Warghat PA. Effect of paediatric rehabilitation in children with Guillain-Barré syndrome: a case series. Cureus [Internet]. 2024; 16(5): e59815. Disponible en: https://doi.org/10.7759/cureus.59815
Estublier B, Colineaux H, Arnaud C, Cintas P, Baudou E, Chaix Y, et al. Long-term outcomes of paediatric Guillain-Barré syndrome. Dev Med Child Neurol [Internet]. 2024; 66(2): 176-186. Disponible en: https://doi.org/10.1111/dmcn.15693
Tomita MR, Buckner K, Saharan S, Persons K, Liao SH. Extended occupational therapy reintegration strategies for a woman with Guillain-Barré syndrome: case report. Am J Occup Ther [Internet]. 2016; 70(4): 7004210010. Disponible en: https://doi.org/10.5014/ajot.2016.017871
McNicholas N, O'Dowd S, McNamara B, O'Toole O. An unusual presentation of Guillain-Barré syndrome in a young man with bilateral upper extremity weakness. BMJ Case Rep [Internet]. 2015: bcr2015210375. Disponible en: https://doi.org/10.1136/bcr-2015-210375
Athanasopoulos KG, Papanastassiou ID, Drinis I, Groumas N, Gerochristou MA, Petropoulou K. A patient with Guillain-Barré syndrome and late recovery after 1 year. J Musculoskelet Neuronal Interact [Internet]. 2019; 19(2): 226-228. Disponible en: https://pmc.ncbi.nlm.nih.gov/articles/PMC6587086/
Salim OJ, Davidson A, Li K, Leach JP, Heath C. Brainstem encephalitis and acute polyneuropathy associated with hepatitis E infection. BMJ Case rep [Internet]. 2017: bcr2017220799. Disponible en: https://doi.org/10.1136/bcr-2017-220799
Alizadeh N, Packer T, Chen YT, Alnasery Y. What we know about fatigue self-management programs for people living with chronic conditions: a scoping review. Patient Educ Couns [Internet]. 2023; 114: 107866. Disponible en: https://doi.org/10.1016/j.pec.2023.107866
Chehebar DM, Scott KR, Kothari MJ. Guillain-Barré syndrome: a review and analysis of current neurorehabilitation approaches and outcomes. Crit Rev Phys Rehabil Med [Internet]. 2006; 18(4): 283-302. Disponible en: https://doi.org/10.1615/CritRevPhysRehabilMed.v18.i4.10
Ng YS, Lo YL, Lim PA. Characteristics and acute rehabilitation of Guillain-Barré syndrome in Singapore. Ann Acad Med Singap [Internet]. 2004; 33(3): 314-319. Disponible en: https://pubmed.ncbi.nlm.nih.gov/15175771/
Atkins MS, Baumgarten JM, Yasuda YL, Adkins R, Waters RL, Leung P, et al. Mobile arm supports: evidence-based benefits and criteria for use. J Spinal Cord Med [Internet]. 2008; 31(4): 388-393. Disponible en: https://doi.org/10.1080/10790268.2008.11760741
Connors C, McNeill S, Hrdlicka HC. Occupational and physical therapy strategies for the rehabilitation of COVID-19-related Guillain-Barré syndrome in the long-term acute care hospital setting: case report. JMIR Rehabil Assist Technol [Internet]. 2022; 9(1): e30794. https://doi.org/10.2196/30794
Hughes RA. Guillain-Barré syndrome: history, pathogenesis, treatment, and future directions. Eur J Neurol [Internet]. 2024; 31(11): e16346. Disponible en: https://doi.org/10.1111/ene.16346
Levison LS, Thomsen RW, Andersen H. Increased mortality following Guillain-Barré syndrome: a population-based cohort study. Eur J Neurol [Internet]. 2022; 29(4): 1145-1154. Disponible en: https://doi.org/10.1111/ene.15204
Kossi O, Raats J, Wellens J, Duckaert M, De Baets S, Van de Velde D, et al. Efficacy of rehabilitation interventions evaluated in common neurological conditions in improving participation outcomes: a systematic review. Clin Rehabil [Internet]. 2024; 38(1): 47-59. Disponible en: https://doi.org/10.1177/02692155231191383
Juckett LA, Wengerd LR, Faieta J, Griffin CE. Evidence-based practice implementation in stroke rehabilitation: a scoping review of barriers and facilitators. Am J Occup Ther [Internet]. 2020; 74(1): 7401205050. Disponible en: https://doi.org/10.5014/ajot.2020.035485
Shen Y, Jiang L, Lai J, Hu J, Liang F, Zhang X, et al. A comprehensive review of rehabilitation approaches for traumatic brain injury: efficacy and outcomes. Front Neurol [Internet]. 2025; 16: 1608645. Disponible en: https://doi.org/10.3389/fneur.2025.1608645
Wade D. Rehabilitation — a new approach. Part four: a new paradigm, and its implications. Clin Rehabil [Internet]. 2016; 30(2): 109-118. Disponible en: https://doi.org/10.1177/0269215515601177
Cieza A, Causey K, Kamenov K, Hanson SW, Chatterji S, Vos T. Global estimates of the need for rehabilitation based on the Global Burden of Disease Study 2019: a systematic analysis for the global burden of disease study 2019. Lancet [Internet]. 2021; 396(10267): 2006-2017. Disponible en: https://doi.org/10.1016/S0140-6736(20)32340-0
World Health Organization. International Classification of Functioning, Disability and Health (ICF) [Internet]. Geneva: WHO; 2001. Disponible en: https://www.who.int/standards/classifications/international-classification-of-functioning-disability-and-health
Hammell KW. Participation and occupation: the need for a human rights perspective. Can J Occup Ther [Internet]. 2015; 82(1): 4-8. Disponible en: https://doi.org/10.1177/0008417414567636
Hoffmann TC, Glasziou PP, Boutron I, Milne R, Perera R, Moher D, et al. Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide. BMJ [Internet]. 2014; 348: g1687. Disponible en: https://doi.org/10.1136/bmj.g1687
Balevi IS, Anziska A. Looking through the mirror of neuroengineering: emerging technologies in neurorehabilitation. Med Res Arch [Internet]. 2024; 12(11). Disponible en: https://doi.org/10.18103/mra.v12i11.5933
Lang CE, Miller AE, Macpherson CE, Bland MD, Holleran CL, Lohse KR. Advancing neurorehabilitation and recovery through human movement quantification via wearable sensing. Neurorehabil Neural Repair [Internet]. 2026: 15459683251412310. Disponible en: https://doi.org/10.1177/15459683251412310
Zhang J, He C. Evidence-based rehabilitation medicine: definition, foundation, practice and development. Med Rev [Internet]. 2024; 4(1): 42-54. Disponible en: https://doi.org/10.1515/mr-2023-0027
World Federation of Occupational Therapists. Guiding principles for the use of evidence in occupational therapy [Internet]. WFOT; 2021. Disponible en: https://wfot.org/resources/guiding-principles-for-the-use-of-evidence-in-occupational-therapy
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Pía Francesca Dennise González Gómez, Francisco José Kroff Trujillo

This work is licensed under a Creative Commons Attribution 4.0 International License.
All articles published in the Revista Herediana de Rehabilitación are under a Creative Commons Reconocimiento 4.0 International license.
The authors retain the copyright and grant the journal the right of first publication, with the work registered with the Creative Commons License, which allows third parties to use what is published whenever they mention the authorship of the work, and to the first publication in this magazine.
Authors can make other independent and additional contractual agreements for the non-exclusive distribution of the version published in this journal, provided they clearly indicate that the work was published in this journal.
The authors can file in the repository of their institution:
The research work or thesis of degree from which the published article derives.
The pre-print version: the version prior to peer review.
The Post-print version: final version after peer review.
The definitive version or final version created by the publisher for publication.











Esta obra está bajo una