Avanços na neurorreabilitação e perspectivas sobre o controle e a aprendizagem motora: revisão de escopo

Autores

  • Karen Ginneth López Hernández Escuela Colombiana de Rehabilitación. Bogotá, Colombia.
  • Zulay Karina Ibarra Velandria Escuela Colombiana de Rehabilitación. Bogotá, Colombia.

DOI:

https://doi.org/10.20453/rhr.v8i2.7271

Palavras-chave:

neurorreabilitação, aprendizagem motora, controle motor, transtornos neurológicos

Resumo

Este artigo apresenta uma revisão de escopo que analisa a relevância da aprendizagem motora como eixo fundamental na reorganização funcional do sistema nervoso, destacando os enfoques explícitos e implícitos como estratégias terapêuticas diferenciadas. O objetivo consistiu em explorar os avanços recentes em neurorreabilitação e analisar as perspectivas atuais sobre o controle e a aprendizagem motora. Foi realizada uma busca inicial de 164 estudos nas bases de dados PubMed, Scopus, Wiley e PEDro, dos quais foram selecionados 42 documentos que atenderam aos critérios de elegibilidade e às diretrizes do Instituto Joanna Briggs (JBI), incluindo ensaios clínicos aleatórios, revisões sistemáticas e literatura cinzenta publicados entre 2015 e 2025. A evidência sugere que intervenções inovadoras, que integram tecnologias emergentes como realidade virtual, interfaces cérebro-computador, estimulação elétrica cerebral não invasiva e gamificação, induzem mudanças plásticas na função cerebral. Determinou-se que a validade dos protocolos de neurorreabilitação depende de prescrições específicas quanto à intensidade, duração e frequência. Destaca-se a necessidade de padronizar protocolos, ampliar o tamanho da amostra em estudos experimentais e validar as intervenções em ambientes clínicos reais, identificando lacunas que orientam futuras pesquisas para modelos integradores, acessíveis e sustentáveis no campo da neurorreabilitação.

Downloads

Não há dados estatísticos.

Biografia do Autor

Karen Ginneth López Hernández, Escuela Colombiana de Rehabilitación. Bogotá, Colombia.

  

Zulay Karina Ibarra Velandria, Escuela Colombiana de Rehabilitación. Bogotá, Colombia.

   

Referências

Leon-Sarmiento FE, Bayona E, Bayona-Prieto J. Neurorrehabilitación: la otra revolución del siglo XXI. Acta Méd Colomb [Internet]. 2009; 34(2): 88-92. Disponible en: http://scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-24482009000200007

Roemmich RT, Bastian AJ. Closing the loop: from motor neuroscience to neurorehabilitation. Annu Rev Neurosci [Internet]. 2018; 41: 415-429. Disponible en: https://doi.org/10.1146/annurev-neuro-080317-062245

Levin MF, Piscitelli D. Motor control: a conceptual framework for rehabilitation. Motor Control [Internet]. 2022; 26(4): 497-517. Disponible en: https://doi.org/10.1123/mc.2022-0026

Maier M, Ballester BR, Verschure PF. Principles of neurorehabilitation after stroke based on motor learning and brain plasticity mechanisms. Front Syst Neurosci [Internet]. 2019; 13: 74. Disponible en: https://doi.org/10.3389/fnsys.2019.00074

Latash ML, Levin MF, Scholz JP, Schöner G. Motor control theories and their applications. Medicina [Internet]. 2010; 46(6): 382-392. Disponible en: https://doi.org/10.3390/medicina46060054

Leech KA, Roemmich RT, Gordon J, Reisman DS, Cherry-Allen KM. Updates in motor learning: implications for physical therapist practice and education. Phys Ther [Internet]. 2022; 102(1): pzab250. Disponible en: https://doi.org/10.1093/ptj/pzab250

Gunduz ME, Bucak B, Keser Z. Advances in stroke neurorehabilitation. J Clin Med [Internet]. 2023; 12(21): 6734. Disponible en: https://doi.org/10.3390/jcm12216734

Iandolo R, Marini F, Semprini M, Laffranchi M, Mugnosso M, Cherif A, et al. Perspectives and challenges in robotic neurorehabilitation. Appl Sci [Internet]. 2019; 9(15): 3183. Disponible en: https://doi.org/10.3390/app9153183

Sucharew H, Macaluso M. Progress notes: methods for research evidence synthesis: the scoping review approach. J Hosp Med [Internet]. 2019; 14(7): 416-418. Disponible en: https://doi.org/10.12788/jhm.3248

Peters MD, Marnie C, Tricco AC, Pollock D, Munn Z, Alexander L, et al. Updated methodological guidance for the conduct of scoping reviews. JBI Evid Synth [Internet]. 2020; 18(10): 2119-2126. Disponible en: https://doi.org/10.11124/JBIES-20-00167

Burduladze N, Jones LP, Jones BD, Pollock D, Munn Z, Alexander L, et al. Exploring power and power sharing in participatory health research partnerships: a scoping review protocol. PLoS ONE [Internet]. 2024; 19(7): e0303799. Disponible en: https://doi.org/10.1371/journal.pone.0303799

Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A. Rayyan—a web and mobile app for systematic reviews. Syst Rev [Internet]. 2016; 5(1): 210. Disponible en: https://doi.org/10.1186/s13643-016-0384-4

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ [Internet]. 2021; 372: n71. Disponible en: https://doi.org/10.1136/bmj.n71

Harada T, Hara M, Matsushita K, Kawakami K, Kawakami K, Anan M, et al. Off-line effects of alpha-frequency transcranial alternating current stimulation on a visuomotor learning task. Brain Behav [Internet]. 2020; 10(9): e01754. Disponible en: https://doi.org/10.1002/brb3.1754

Yang S, Li R, Li H, Xu K, Shi Y, Wang Q, et al. Exploring the use of brain-computer interfaces in stroke neurorehabilitation. Biomed Res Int [Internet]. 2021; 2021: 9967348. Disponible en: https://doi.org/10.1155/2021/9967348

Marino M, Mantini D. Human brain imaging with high-density electroencephalography: techniques and applications. J Physiol [Internet]. 2024; 604(2): 783-812. Disponible en: https://doi.org/10.1113/JP286639

He XK, Sun QQ, Liu HH, Guo XY, Chen C, Chen LD. Timing of acupuncture during LTP-like plasticity induced by paired-associative stimulation. Behav Neurol [Internet]. 2019; 2019(1): 9278270. Disponible en: https://doi.org/10.1155/2019/9278270

Gandolfi M, Sandri A, Menaspà Z, Avanzino L, Pelosin E, Geroin C, et al. How does postural control in patients with functional motor disorders adapt to multitasking-based immersive virtual reality? Mov Disord Clin Pract [Internet]. 2024; 11(4): 337-345. Disponible en: https://doi.org/10.1002/mdc3.13961

Liao WY, Hand BJ, Cirillo J, Sasaki R, Opie GM, Goldsworthy MR, et al. Gamma transcranial alternating current stimulation has frequency-dependent effects on human motor cortex plasticity induced by theta-burst stimulation. Eur J Neurosci [Internet]. 2025; 61(3): e70018. Disponible en: https://doi.org/10.1111/ejn.70018

Pimentel-Ponce M, Romero-Galisteo RP, Palomo-Carrión R, Pinero-Pinto E, Merchán-Baeza JA, Ruiz-Muñoz M, et al. Gamification and neurological motor rehabilitation in children and adolescents: a systematic review. Neurología [Internet]. 2024; 39(1): 63-83. Disponible en: https://doi.org/10.1016/j.nrleng.2023.12.006

Oliveira I, Russo M, Almeida AI, Vourvopoulos A, Mendes Pereira C. Recommendations for combining brain-computer interface, motor imagery, and virtual reality in upper limb stroke rehabilitation: qualitative participatory design study. JMIR Rehabil Assist Technol [Internet]. 2025; 12: e71789. Disponible en: https://doi.org/10.2196/71789

Sihvonen AJ, Särkämö T, Leo V, Tervaniemi M, Altenmüller E, Soinila S. Music-based interventions in neurological rehabilitation. Lancet Neurol [Internet]. 2017; 16(8): 648-660. Disponible en: https://doi.org/10.1016/S1474-4422(17)30168-0

Schachten T, Jansen P. The effects of golf training in patients with stroke: a pilot study. Int Psychogeriatr [Internet]. 2015; 27(5): 865-873. Disponible en: https://doi.org/10.1017/S1041610214002452

Talimkhani MM, Talimkhani A, Dinarvand V, Mohamadi S, Baharlouei H. The effects of multi-session dual-tDCS on the bilateral transfer of motor skill learning in patients with stroke. Clin Neurophysiol Pract [Internet]. 2025;10:236-245. Disponible en: https://doi.org/10.1016/j.cnp.2025.06.005

Grünbaum T, Christensen MS. The functional role of conscious sensation of movement. Neurosci Biobehav Rev [Internet]. 2024; 164: 105813. Disponible en: https://doi.org/10.1016/j.neubiorev.2024.105813

Hardeman LE, van Benten E, Hoogendoorn EM, van Gameren M, Nonnekes J, Roerdink M, et al. Home-based augmented reality exercise for people with parkinson disease: qualitative acceptability study. JMIR Rehabil Assist Technol [Internet]. 2025; 12: e70802. Disponible en: https://doi.org/10.2196/70802

Dutta A, Das A. Platform technology for extended reality biofeedback training under operant conditioning for functional limb weakness: protocol for the coproduction of an at-home solution (React2Home). JMIR Res Protoc [Internet]. 2025; 14: e70620. Disponible en: https://doi.org/10.2196/70620

Lv Z, Guo J. Virtual reality neurorehabilitation. Int J Ment Health Promot [Internet]. 2022; 24(3): 287-310. Disponible en: https://doi.org/10.32604/ijmhp.2022.019829

Antonioni A, Raho EM, Straudi S, Granieri E, Koch G, Fadiga L. The cerebellum and the mirror neuron system: a matter of inhibition? from neurophysiological evidence to neuromodulatory implications. A narrative review. Neurosci Biobehav Rev [Internet]. 2024; 164: 105830. Disponible en: https://doi.org/10.1016/j.neubiorev.2024.105830

Corrini C, Gervasoni E, Perini G, Cosentino C, Putzolu M, Montesano A, et al. Mobility and balance rehabilitation in multiple sclerosis: a systematic review and dose-response meta-analysis. Mult Scler Relat Disord [Internet]. 2023; 69: 104424. Disponible en:10.1016/j.msard.2022.104424

Huang H, Bach JR, Sharma HS, Saberi H, Jeon SR, Guo X, et al. The 2022 yearbook of neurorestoratology. J Neurorestoratology [Internet]. 2023; 11(2): 100054. Disponible en: https://doi.org/10.1016/j.jnrt.2023.100054

Zaragoza-Mezquita M, Felix-Esbrí S, Sebastián-Tirado A, Guinot P, Melero C, Forn C, et al. Exploring the potential of immersive Virtual Reality (VR) as a tool to enhance cognitive functions and alleviate clinical symptoms in Multiple Sclerosis (MS): enhancing cognitive functions in multiple sclerosis using virtual reality. Mult Scler Relat Disord [Internet]. 2025; 93: 106235. Disponible en: https://doi.org/10.1016/j.msard.2024.106235

Hussain M, Foglia SD, Park J, Ramdeo KR, Adams FC, Drapeau CC, et al. Ipsilateral contraction increases map area and decreases motor threshold for contralateral hand muscle. Neuroscience [Internet]. 2025; 586: 144-151. Disponible en: https://doi.org/10.1016/j.neuroscience.2025.09.034

Benadduci M, Franceschetti C, Marziali RA, Frese S, Sándor PS, Tombolesi V, et al. An integrated Virtual Reality-based telerehabilitation platform to support recovery and maintenance of functional abilities among older adults: protocol for a usability and acceptability study. JMIR Res Protoc [Internet]. 2025; 14: e88023. Disponible en: https://doi.org/10.2196/88023

Del Rosario-Montejo O, Molina-Rueda F, Muñoz-Lasa S, Alguacil-Diego IM. Efectividad de la terapia ecuestre en niños con retraso psicomotor. Neurología [Internet]. 2015; 30(7): 425-432. Disponible en: https://doi.org/10.1016/j.nrl.2013.12.023

Champagne PL, Blanchette AK, Schneider C. Continuous, and not intermittent, theta-burst stimulation of the unlesioned hemisphere improved brain and hand function in chronic stroke: a case study. Brain Disorders [Internet]. 2023; 9: 100062. Disponible en: https://doi.org/10.1016/j.dscb.2022.100062

Bonini L, Rotunno C, Arcuri E, Gallese V. Mirror neurons 30 years later: implications and applications. Trends Cogn Sci [Internet]. 2022; 26(9): 767-781. Disponible en: https://doi.org/10.1016/j.tics.2022.06.003

Hernandez ME, Motl RW, Foley FW, Izzetoglu M, Wagshul M, Holtzer R. Comparison of practice-related changes in dual task walking performance and neural efficiency between older adults with progressive and relapsing-remitting multiple sclerosis. Mult Scler Relat Disord [Internet]. 2025; 93: 106224. Disponible en: https://doi.org/10.1016/j.msard.2024.106224

Verschure PF, Páscoa dos Santos F, Sharma V. Redefining stroke rehabilitation: mobilizing the embodied goal-oriented brain. Curr Opin Neurobiol [Internet]. 2023; 83: 102807. Disponible en: https://doi.org/10.1016/j.conb.2023.102807

Trindade MF, Carvalho R, Silva A. Motor imagery combined with action observation integrated with physiotherapy in patients with Parkinson disease: repercussions on functional capacity-case series study. J Bodyw Mov Ther [Internet]. 2025; 44: 161-169. Disponible en: https://doi.org/10.1016/j.jbmt.2025.05.071

Brassel S, Power E, Campbell A, Brunner M, Togher L. Recommendations for the design and implementation of virtual reality for acquired brain injury rehabilitation: systematic review. J Med Internet Res [Internet]. 2021; 23(7): e26344. Disponible en: https://doi.org/10.2196/26344

Gazerani P. The neuroplastic brain: current breakthroughs and emerging frontiers. Brain Res [Internet]. 2025; 1858: 149643. Disponible en: https://doi.org/10.1016/j.brainres.2025.149643

Fukumoto Y, Todo M, Bizen H, Kimura D, Suzuki T. Causal relationships between brain and spinal motor neuron excitability during motor imagery: using NIRS and evoked electromyogram study. Neuroimage Rep [Internet]. 2022; 2(1): 100083. Disponible en: https://doi.org/10.1016/j.ynirp.2022.100083

Huang H, Sanberg PR, Sharma HS, Bach JR, Saberi H, Shetty AK, et al. The 2024 yearbook of J Neurorestoratology. Neurorestoratology [Internet]. 2025; 13(6): 100250. Disponible en: https://doi.org/10.1016/j.jnrt.2025.100250

Chen M, Chen Z, Xiao X, Zhou L, Fu R, Jiang X, et al. Corticospinal circuit neuroplasticity may involve silent synapses: Implications for functional recovery facilitated by neuromodulation after spinal cord injury. IBRO Neurosci Rep [Internet]. 2023; 14: 185-194. Disponible en: https://doi.org/10.1016/j.ibneur.2022.08.005

Tavazzi E, Bergsland N, Pirastru A, Cazzoli M, Blasi V, Baglio F. MRI markers of functional connectivity and tissue microstructure in stroke-related motor rehabilitation: a systematic review. Neuroimage Clin [Internet]. 2022; 33: 102931. Disponible en: https://doi.org/10.1016/j.nicl.2021.102931

Akaiwa M, Kurokawa R, Matsuda Y, Sugawara Y, Kosuge R, Saito H, et al. Enhancement of beta rebound elicited by proprioceptive stimulation in the sensorimotor cortex by transcranial alternating current stimulation matched to the dominant beta frequency. Neurosci Res [Internet]. 2025; 216: 104896. Disponible en: https://doi.org/10.1016/j.neures.2025.03.008

Wu J, Zhang H, Chen Z, Fu R, Yang H, Zeng H, et al. Benefits of virtual reality balance training for patients with Parkinson disease: systematic review, meta-analysis, and meta-regression of a randomized controlled trial. JMIR Serious Games [Internet]. 2022; 10(1): e30882. Disponible en: https://doi.org/10.2196/30882

Tyler M, Skinner K, Prabhakaran V, Kaczmarek K, Danilov Y. Translingual neurostimulation for the treatment of chronic symptoms due to mild-to-moderate traumatic brain injury. Arch Rehabil Res Clin Transl [Internet]. 2019; 1(3-4): 100026. Disponible en: https://doi.org/10.1016/j.arrct.2019.100026

Huo C, Xu G, Li W, Xie H, Zhang T, Liu Y, et al. A review on functional near-infrared spectroscopy and application in stroke rehabilitation. Med Nov Technol Devices. 2021; 11: 100064. Disponible en: https://doi.org/10.1016/j.medntd.2021.100064

Burtscher J, Moraud EM, Malatesta D, Millet GP, Bally JF, Patoz A. Exercise and gait/movement analyses in treatment and diagnosis of Parkinson's disease. Ageing Res Rev [Internet]. 2024; 93: 102147. Disponible en:10.1016/j.arr.2023.102147

Han X, Zhu Z, Luan J, Lv P, Xin X, Zhang X, et al. Effects of repetitive transcranial magnetic stimulation and their underlying neural mechanisms evaluated with magnetic resonance imaging-based brain connectivity network analyses. Eur J Radiol Open [Internet]. 2023; 10: 100495. Disponible en: https://doi.org/10.1016/j.ejro.2023.100495

Gabriel CL, Pires IM, Coelho PJ, Zdravevski E, Lameski P, Mewada H, et al. Mobile and wearable technologies for the analysis of Ten Meter Walk Test: a concise systematic review. Heliyon [Internet]. 2023; 9(6): e16599. Disponible en: https://doi.org/10.1016/j.heliyon.2023.e16599

Panuccio G, Semprini M, Chiappalone M. Intelligent biohybrid systems for functional brain repair. New Horiz Transl Med [Internet]. 2016; 3(3-4): 162-174. Disponible en: https://doi.org/10.1016/j.nhtm.2016.10.001

Sureshkumar S, Yogarajan K. Technological advancement to neurorehabilitation [Internet]. Neurocosm Int J [Internet]. 2021; 2(1): 17-22. Disponible en: https://www.neurocosm.net/article/technological-advancement-neurorehabilitation.pdf

Publicado

2025-12-31

Como Citar

López Hernández, K. G., & Ibarra Velandria, Z. K. (2025). Avanços na neurorreabilitação e perspectivas sobre o controle e a aprendizagem motora: revisão de escopo. Revista Herediana De Rehabilitación, 8(2), e7271. https://doi.org/10.20453/rhr.v8i2.7271

Edição

Seção

ARTÍCULOS DE REVISIÓN